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Of note, despite the high CVD risk in the patient populations in both LEADER and Trial to Evaluate Cardiovascular and Other Long-term Outcomes With Semaglutide in Subjects With Type 2 Diabetes (SUSTAIN-6), all cardiovascular risk factors, including blood pressure and LDL cholesterol, were well controlled at baseline, consistent with the high number of patients receiving statins, ACE inhibitors, angiotensin receptor blockers, and aspirin therapy

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Dosing:Low-Dose

Creating a sequence of target trials We emulated a sequence of 135 target trials between January 2013 and March 2024